S. Boulardii Probiotics For SIBO – Do They Help?
S. Boulardii Probiotics For SIBO - Do They Help?
Florastor contains a unique probiotic strain of yeast-origin, Saccharomyces boulardii CNCM I-745, which is antibiotic resistant and well-studied for a wide variety of clinical purposes.
S. Boulardii Probiotics For SIBO - Do They Help?
These include:
Reducing the risk/severity of acute & antibiotic associated diarrhea
Restoring the microbiome after disruption from antibiotics or infection
Contributing to the treatment process in infections such as H Pylori and Difficile
S. Boulardii Probiotics For SIBO - Do They Help?
In today’s blog post, my scientific gaze turns towards the use of S. Boulardii as a complimentary management strategy in SIBO (small intestinal bacterial overgrowth), which is defined as a quantity of bacteria in the digestive tract beyond a threshold level.
S. Boulardii Probiotics For SIBO - Do They Help?
Recent years has seen an uptick in clinical trials in this area, so I’ve teamed up with Florastor to take a closer look at what science has to say in this area.
S. Boulardii Probiotics For SIBO - Do They Help?
SB For IBS-D with SIBO
A recently published trial out of Digestive Diseases journal explored the use of Saccharomyces boulardii CNCM I-745 in patients living with IBS-D and SIBO.
S. Boulardii Probiotics For SIBO - Do They Help?
In this study researchers compared the effects of dietary guidance alone or in combination with probiotic supplementation.
S. Boulardii Probiotics For SIBO - Do They Help?
They determined that the group receiving both S. Boulardii and dietary advice had better outcomes than the group receiving dietary advice alone.
S. Boulardii Probiotics For SIBO - Do They Help?
This included:
A decrease in SIBO severity (as measured via decreases in hydrogen excretion test)
A decrease in IBS severity scores
A decrease in diarrhea frequency
In this context, with a great safety profile, S. Boulardii was demonstrated to improve outcomes in IBS-D accompanied by SIBO – with similar results also being noted in an American Gastroenterological Association pilot study.
SB For SIBO In Decompensated Cirrhosis
In a 2022 trial out of Current Developments In Nutrition, patients with decompensated (advanced) cirrhosis and SIBO were provided either S. Boulardii or placebo in combination with standard therapy.
No adverse effects were noted in the probiotic group and significantly less participants had detectable SIBO at the conclusion of the 3-month trial period in the probiotic vs control group, indicating the promise of…
..